Promising research in treating alcoholism....

[someone in need]

Alcohol Effects Can Be Blocked, Scientists Say




A team of scientists at The Scripps Research Institute has described
the cellular mechanism underlying the brain's response to alcohol,
which suggests a possible method for treating alcoholism.

This work, published in the latest issue of the journal Science, ties
together the effect of the brain peptide corticotropin releasing
factor (CRF) with alcohol. Both appear to influence neurotransmission
in the amygdala, the so-called pleasure center of the brain, by
increasing the transmission of one particular neurotransmitter called
gamma amino butyric acid (GABA).

"There is a strong relationship between drugs of abuse, stress, and
the amygdala," says Neuropharmacology Professor George Siggins, who
led the research.

The research suggests that compounds that block CRF receptors might be
a potential new therapeutic for alcoholics, who struggle to stop
drinking.

Drugs that block CRF receptors are already being looked at by
scientists as potential treatments for other psychiatric conditions
such as depression, panic disorder, and post-traumatic stress
disorder--conditions that also involve CRF in the amygdala.

In the latest research, Siggins and his colleagues looked at the
effect of alcohol and a common stress-related neuropeptide on a
neurotransmitter called gamma amino butyric acid (GABA).
Sponsored Links

Meth addiction treatmentMedical approach for treating meth addiction.
3 day program start.www.prometainfo.com

Home Addiction RecoveryEffective, affordable, confidential option to
conventional treatment.www.homerecovery.net

Drug Addiction HelpWe will help you find solutions for your abuse
situation for free.www.PacHills.com
GABA is the main inhibitory neurotransmitter in the brain, and neurons
in every brain region use GABA to fine-tune signaling throughout the
nervous system.

Scientists have known for several years that alcohol produces many of
its intoxicating actions through facilitation of GABA receptor
function, and preclinical studies of alcohol dependence have shown
that GABAergic activity decreases during alcohol withdrawal and
protracted abstinence--the initial post-acute withdrawal period after
the cessation of drinking during which a person is especially
vulnerable to relapse. These GABAergic activity changes are probably a
major cause of relapse to alcoholism in individuals undergoing
treatment.

Previous studies have also shown that alcohol enhances GABA
neurotransmission in the amygdala, the so-called pleasure center of
the brain. Interestingly, the brain corticotropin releasing factor
(CRF) stress system also increases GABA transmission in the amygdala.

CRF is a common peptide in the brain that is responsible for
activating the hypothalamic-pituitary-adrenal stress response and in
the amygdala for activating sympathetic and behavioral responses to
stressors. CRF is found in lots of different parts of the brain and is
known to be involved in the brain in response to stress, anxiety, and
depression.

Significantly, the CRF system also seems to be central to alcoholism,
and scientists at Scripps Research and elsewhere have shown that CRF
is involved in the transition from alcohol use to alcohol dependence.
Scripps Research Professor George Koob and his colleagues found
recently that levels of CRF increase in brains treated with alcohol.
Other studies have shown that CRF levels increase when animals are
withdrawing from alcohol as well--a situation analogous to an
alcoholic's protracted abstinence.

In their latest paper, Siggins and his colleagues show, at the
cellular level, how alcohol and CRF interact. When neurons are exposed
to alcohol, says Siggins, they release CRF, and this causes the
release of GABA in the amygdala. And when the CRF receptor is removed
altogether (by genetic knock out), the effect of alcohol and CRF on
GABA neurotransmission is lost.

Siggins and his colleagues say that this suggests a cellular mechanism
underlying involvement of CRF in alcohol's behavioral and motivational
effects. During withdrawal, CRF levels increase and these changes may
persist for a long time.

It also suggests a possible way of treating alcoholism -- using CRF
antagonists, or compounds that block the effects of CRF. In the
current study, when the scientists applied an antagonist of CRF, they
found that alcohol no longer had an effect.

"Not only did the antagonists block the effect of CRF in enhancing
GABA transmission, it also blocked the effect of alcohol," says
Siggins. "The response was totally gone*alcohol no longer did
anything.

[WACO]

About as effective as a frontal lobotomy?

someone in need wrote:
> Alcohol Effects Can Be Blocked, Scientists Say
>
>
>
>
> A team of scientists at The Scripps Research Institute has described
> the cellular mechanism underlying the brain's response to alcohol,
> which suggests a possible method for treating alcoholism.
>
> This work, published in the latest issue of the journal Science, ties
> together the effect of the brain peptide corticotropin releasing
> factor (CRF) with alcohol. Both appear to influence neurotransmission
> in the amygdala, the so-called pleasure center of the brain, by
> increasing the transmission of one particular neurotransmitter called
> gamma amino butyric acid (GABA).
>
> "There is a strong relationship between drugs of abuse, stress, and
> the amygdala," says Neuropharmacology Professor George Siggins, who
> led the research.
>
> The research suggests that compounds that block CRF receptors might be
> a potential new therapeutic for alcoholics, who struggle to stop
> drinking.
>
> Drugs that block CRF receptors are already being looked at by
> scientists as potential treatments for other psychiatric conditions
> such as depression, panic disorder, and post-traumatic stress
> disorder--conditions that also involve CRF in the amygdala.
>
> In the latest research, Siggins and his colleagues looked at the
> effect of alcohol and a common stress-related neuropeptide on a
> neurotransmitter called gamma amino butyric acid (GABA).
> Sponsored Links
>
> Meth addiction treatmentMedical approach for treating meth addiction.
> 3 day program start.www.prometainfo.com
>
> Home Addiction RecoveryEffective, affordable, confidential option to
> conventional treatment.www.homerecovery.net
>
> Drug Addiction HelpWe will help you find solutions for your abuse
> situation for free.www.PacHills.com
> GABA is the main inhibitory neurotransmitter in the brain, and neurons
> in every brain region use GABA to fine-tune signaling throughout the
> nervous system.
>
> Scientists have known for several years that alcohol produces many of
> its intoxicating actions through facilitation of GABA receptor
> function, and preclinical studies of alcohol dependence have shown
> that GABAergic activity decreases during alcohol withdrawal and
> protracted abstinence--the initial post-acute withdrawal period after
> the cessation of drinking during which a person is especially
> vulnerable to relapse. These GABAergic activity changes are probably a
> major cause of relapse to alcoholism in individuals undergoing
> treatment.
>
> Previous studies have also shown that alcohol enhances GABA
> neurotransmission in the amygdala, the so-called pleasure center of
> the brain. Interestingly, the brain corticotropin releasing factor
> (CRF) stress system also increases GABA transmission in the amygdala.
>
> CRF is a common peptide in the brain that is responsible for
> activating the hypothalamic-pituitary-adrenal stress response and in
> the amygdala for activating sympathetic and behavioral responses to
> stressors. CRF is found in lots of different parts of the brain and is
> known to be involved in the brain in response to stress, anxiety, and
> depression.
>
> Significantly, the CRF system also seems to be central to alcoholism,
> and scientists at Scripps Research and elsewhere have shown that CRF
> is involved in the transition from alcohol use to alcohol dependence.
> Scripps Research Professor George Koob and his colleagues found
> recently that levels of CRF increase in brains treated with alcohol.
> Other studies have shown that CRF levels increase when animals are
> withdrawing from alcohol as well--a situation analogous to an
> alcoholic's protracted abstinence.
>
> In their latest paper, Siggins and his colleagues show, at the
> cellular level, how alcohol and CRF interact. When neurons are exposed
> to alcohol, says Siggins, they release CRF, and this causes the
> release of GABA in the amygdala. And when the CRF receptor is removed
> altogether (by genetic knock out), the effect of alcohol and CRF on
> GABA neurotransmission is lost.
>
> Siggins and his colleagues say that this suggests a cellular mechanism
> underlying involvement of CRF in alcohol's behavioral and motivational
> effects. During withdrawal, CRF levels increase and these changes may
> persist for a long time.
>
> It also suggests a possible way of treating alcoholism -- using CRF
> antagonists, or compounds that block the effects of CRF. In the
> current study, when the scientists applied an antagonist of CRF, they
> found that alcohol no longer had an effect.
>
> "Not only did the antagonists block the effect of CRF in enhancing
> GABA transmission, it also blocked the effect of alcohol," says
> Siggins. "The response was totally gone*alcohol no longer did
> anything.

[someone in need]

Perhaps you can be the "control patient" that is you get the lobotomy
and compare results with those using the CRH blocker.

What is the basis of your comment/conclusion?


On Sat, 13 Aug 2005 04:44:00 GMT, WACO
<WasACucumberOnce@NowI'mSober.com> wrote:

>About as effective as a frontal lobotomy?
>
>someone in need wrote:
>> Alcohol Effects Can Be Blocked, Scientists Say
>>
>>
>>
>>
>> A team of scientists at The Scripps Research Institute has described
>> the cellular mechanism underlying the brain's response to alcohol,
>> which suggests a possible method for treating alcoholism.
>>
>> This work, published in the latest issue of the journal Science, ties
>> together the effect of the brain peptide corticotropin releasing
>> factor (CRF) with alcohol. Both appear to influence neurotransmission
>> in the amygdala, the so-called pleasure center of the brain, by
>> increasing the transmission of one particular neurotransmitter called
>> gamma amino butyric acid (GABA).
>>
>> "There is a strong relationship between drugs of abuse, stress, and
>> the amygdala," says Neuropharmacology Professor George Siggins, who
>> led the research.
>>
>> The research suggests that compounds that block CRF receptors might be
>> a potential new therapeutic for alcoholics, who struggle to stop
>> drinking.
>>
>> Drugs that block CRF receptors are already being looked at by
>> scientists as potential treatments for other psychiatric conditions
>> such as depression, panic disorder, and post-traumatic stress
>> disorder--conditions that also involve CRF in the amygdala.
>>
>> In the latest research, Siggins and his colleagues looked at the
>> effect of alcohol and a common stress-related neuropeptide on a
>> neurotransmitter called gamma amino butyric acid (GABA).
>> Sponsored Links
>>
>> Meth addiction treatmentMedical approach for treating meth addiction.
>> 3 day program start.www.prometainfo.com
>>
>> Home Addiction RecoveryEffective, affordable, confidential option to
>> conventional treatment.www.homerecovery.net
>>
>> Drug Addiction HelpWe will help you find solutions for your abuse
>> situation for free.www.PacHills.com
>> GABA is the main inhibitory neurotransmitter in the brain, and neurons
>> in every brain region use GABA to fine-tune signaling throughout the
>> nervous system.
>>
>> Scientists have known for several years that alcohol produces many of
>> its intoxicating actions through facilitation of GABA receptor
>> function, and preclinical studies of alcohol dependence have shown
>> that GABAergic activity decreases during alcohol withdrawal and
>> protracted abstinence--the initial post-acute withdrawal period after
>> the cessation of drinking during which a person is especially
>> vulnerable to relapse. These GABAergic activity changes are probably a
>> major cause of relapse to alcoholism in individuals undergoing
>> treatment.
>>
>> Previous studies have also shown that alcohol enhances GABA
>> neurotransmission in the amygdala, the so-called pleasure center of
>> the brain. Interestingly, the brain corticotropin releasing factor
>> (CRF) stress system also increases GABA transmission in the amygdala.
>>
>> CRF is a common peptide in the brain that is responsible for
>> activating the hypothalamic-pituitary-adrenal stress response and in
>> the amygdala for activating sympathetic and behavioral responses to
>> stressors. CRF is found in lots of different parts of the brain and is
>> known to be involved in the brain in response to stress, anxiety, and
>> depression.
>>
>> Significantly, the CRF system also seems to be central to alcoholism,
>> and scientists at Scripps Research and elsewhere have shown that CRF
>> is involved in the transition from alcohol use to alcohol dependence.
>> Scripps Research Professor George Koob and his colleagues found
>> recently that levels of CRF increase in brains treated with alcohol.
>> Other studies have shown that CRF levels increase when animals are
>> withdrawing from alcohol as well--a situation analogous to an
>> alcoholic's protracted abstinence.
>>
>> In their latest paper, Siggins and his colleagues show, at the
>> cellular level, how alcohol and CRF interact. When neurons are exposed
>> to alcohol, says Siggins, they release CRF, and this causes the
>> release of GABA in the amygdala. And when the CRF receptor is removed
>> altogether (by genetic knock out), the effect of alcohol and CRF on
>> GABA neurotransmission is lost.
>>
>> Siggins and his colleagues say that this suggests a cellular mechanism
>> underlying involvement of CRF in alcohol's behavioral and motivational
>> effects. During withdrawal, CRF levels increase and these changes may
>> persist for a long time.
>>
>> It also suggests a possible way of treating alcoholism -- using CRF
>> antagonists, or compounds that block the effects of CRF. In the
>> current study, when the scientists applied an antagonist of CRF, they
>> found that alcohol no longer had an effect.
>>
>> "Not only did the antagonists block the effect of CRF in enhancing
>> GABA transmission, it also blocked the effect of alcohol," says
>> Siggins. "The response was totally gone*alcohol no longer did
>> anything.

[WACO]

someone in need wrote:
> Perhaps you can be the "control patient" that is you get the lobotomy
> and compare results with those using the CRH blocker.
>
> What is the basis of your comment/conclusion?

When a person needs a "pill" to justify their behavior and actions its a
sad way to live life. Alcoholism is as much a disease as biting ones nails.
>
>
> On Sat, 13 Aug 2005 04:44:00 GMT, WACO
> <WasACucumberOnce@NowI'mSober.com> wrote:
>
>
>>About as effective as a frontal lobotomy?
>>
>>someone in need wrote:
>>
>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>
>>>
>>>
>>>
>>>A team of scientists at The Scripps Research Institute has described
>>>the cellular mechanism underlying the brain's response to alcohol,
>>>which suggests a possible method for treating alcoholism.
>>>
>>>This work, published in the latest issue of the journal Science, ties
>>>together the effect of the brain peptide corticotropin releasing
>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>in the amygdala, the so-called pleasure center of the brain, by
>>>increasing the transmission of one particular neurotransmitter called
>>>gamma amino butyric acid (GABA).
>>>
>>>"There is a strong relationship between drugs of abuse, stress, and
>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>led the research.
>>>
>>>The research suggests that compounds that block CRF receptors might be
>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>drinking.
>>>
>>>Drugs that block CRF receptors are already being looked at by
>>>scientists as potential treatments for other psychiatric conditions
>>>such as depression, panic disorder, and post-traumatic stress
>>>disorder--conditions that also involve CRF in the amygdala.
>>>
>>>In the latest research, Siggins and his colleagues looked at the
>>>effect of alcohol and a common stress-related neuropeptide on a
>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>Sponsored Links
>>>
>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>3 day program start.www.prometainfo.com
>>>
>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>conventional treatment.www.homerecovery.net
>>>
>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>situation for free.www.PacHills.com
>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>in every brain region use GABA to fine-tune signaling throughout the
>>>nervous system.
>>>
>>>Scientists have known for several years that alcohol produces many of
>>>its intoxicating actions through facilitation of GABA receptor
>>>function, and preclinical studies of alcohol dependence have shown
>>>that GABAergic activity decreases during alcohol withdrawal and
>>>protracted abstinence--the initial post-acute withdrawal period after
>>>the cessation of drinking during which a person is especially
>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>major cause of relapse to alcoholism in individuals undergoing
>>>treatment.
>>>
>>>Previous studies have also shown that alcohol enhances GABA
>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>
>>>CRF is a common peptide in the brain that is responsible for
>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>the amygdala for activating sympathetic and behavioral responses to
>>>stressors. CRF is found in lots of different parts of the brain and is
>>>known to be involved in the brain in response to stress, anxiety, and
>>>depression.
>>>
>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>is involved in the transition from alcohol use to alcohol dependence.
>>>Scripps Research Professor George Koob and his colleagues found
>>>recently that levels of CRF increase in brains treated with alcohol.
>>>Other studies have shown that CRF levels increase when animals are
>>>withdrawing from alcohol as well--a situation analogous to an
>>>alcoholic's protracted abstinence.
>>>
>>>In their latest paper, Siggins and his colleagues show, at the
>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>GABA neurotransmission is lost.
>>>
>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>effects. During withdrawal, CRF levels increase and these changes may
>>>persist for a long time.
>>>
>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>antagonists, or compounds that block the effects of CRF. In the
>>>current study, when the scientists applied an antagonist of CRF, they
>>>found that alcohol no longer had an effect.
>>>
>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>GABA transmission, it also blocked the effect of alcohol," says
>>>Siggins. "The response was totally gone*alcohol no longer did
>>>anything.
>
>

[someone in need]

So therefore a schitzophrenic really must not take lithium to help
control their behavior?



On Sat, 13 Aug 2005 17:30:56 GMT, WACO
<WasACucumberOnce@NowI'mSober.com> wrote:

>someone in need wrote:
>> Perhaps you can be the "control patient" that is you get the lobotomy
>> and compare results with those using the CRH blocker.
>>
>> What is the basis of your comment/conclusion?
>
>When a person needs a "pill" to justify their behavior and actions its a
>sad way to live life. Alcoholism is as much a disease as biting ones nails.
>>
>>
>> On Sat, 13 Aug 2005 04:44:00 GMT, WACO
>> <WasACucumberOnce@NowI'mSober.com> wrote:
>>
>>
>>>About as effective as a frontal lobotomy?
>>>
>>>someone in need wrote:
>>>
>>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>>
>>>>
>>>>
>>>>
>>>>A team of scientists at The Scripps Research Institute has described
>>>>the cellular mechanism underlying the brain's response to alcohol,
>>>>which suggests a possible method for treating alcoholism.
>>>>
>>>>This work, published in the latest issue of the journal Science, ties
>>>>together the effect of the brain peptide corticotropin releasing
>>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>>in the amygdala, the so-called pleasure center of the brain, by
>>>>increasing the transmission of one particular neurotransmitter called
>>>>gamma amino butyric acid (GABA).
>>>>
>>>>"There is a strong relationship between drugs of abuse, stress, and
>>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>>led the research.
>>>>
>>>>The research suggests that compounds that block CRF receptors might be
>>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>>drinking.
>>>>
>>>>Drugs that block CRF receptors are already being looked at by
>>>>scientists as potential treatments for other psychiatric conditions
>>>>such as depression, panic disorder, and post-traumatic stress
>>>>disorder--conditions that also involve CRF in the amygdala.
>>>>
>>>>In the latest research, Siggins and his colleagues looked at the
>>>>effect of alcohol and a common stress-related neuropeptide on a
>>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>>Sponsored Links
>>>>
>>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>>3 day program start.www.prometainfo.com
>>>>
>>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>>conventional treatment.www.homerecovery.net
>>>>
>>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>>situation for free.www.PacHills.com
>>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>>in every brain region use GABA to fine-tune signaling throughout the
>>>>nervous system.
>>>>
>>>>Scientists have known for several years that alcohol produces many of
>>>>its intoxicating actions through facilitation of GABA receptor
>>>>function, and preclinical studies of alcohol dependence have shown
>>>>that GABAergic activity decreases during alcohol withdrawal and
>>>>protracted abstinence--the initial post-acute withdrawal period after
>>>>the cessation of drinking during which a person is especially
>>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>>major cause of relapse to alcoholism in individuals undergoing
>>>>treatment.
>>>>
>>>>Previous studies have also shown that alcohol enhances GABA
>>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>>
>>>>CRF is a common peptide in the brain that is responsible for
>>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>>the amygdala for activating sympathetic and behavioral responses to
>>>>stressors. CRF is found in lots of different parts of the brain and is
>>>>known to be involved in the brain in response to stress, anxiety, and
>>>>depression.
>>>>
>>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>>is involved in the transition from alcohol use to alcohol dependence.
>>>>Scripps Research Professor George Koob and his colleagues found
>>>>recently that levels of CRF increase in brains treated with alcohol.
>>>>Other studies have shown that CRF levels increase when animals are
>>>>withdrawing from alcohol as well--a situation analogous to an
>>>>alcoholic's protracted abstinence.
>>>>
>>>>In their latest paper, Siggins and his colleagues show, at the
>>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>>GABA neurotransmission is lost.
>>>>
>>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>>effects. During withdrawal, CRF levels increase and these changes may
>>>>persist for a long time.
>>>>
>>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>>antagonists, or compounds that block the effects of CRF. In the
>>>>current study, when the scientists applied an antagonist of CRF, they
>>>>found that alcohol no longer had an effect.
>>>>
>>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>>GABA transmission, it also blocked the effect of alcohol," says
>>>>Siggins. "The response was totally gone*alcohol no longer did
>>>>anything.
>>
>>

[WACO]

If a schizophrenia was caused by voluntarily ingesting something, yes, but
it's not. Next comparison of apples to oranges please.

someone in need wrote:
> So therefore a schitzophrenic really must not take lithium to help
> control their behavior?
>
>
>
> On Sat, 13 Aug 2005 17:30:56 GMT, WACO
> <WasACucumberOnce@NowI'mSober.com> wrote:
>
>
>>someone in need wrote:
>>
>>>Perhaps you can be the "control patient" that is you get the lobotomy
>>>and compare results with those using the CRH blocker.
>>>
>>>What is the basis of your comment/conclusion?
>>
>>When a person needs a "pill" to justify their behavior and actions its a
>>sad way to live life. Alcoholism is as much a disease as biting ones nails.
>>
>>>
>>>On Sat, 13 Aug 2005 04:44:00 GMT, WACO
>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>
>>>
>>>
>>>>About as effective as a frontal lobotomy?
>>>>
>>>>someone in need wrote:
>>>>
>>>>
>>>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>>>
>>>>>
>>>>>
>>>>>
>>>>>A team of scientists at The Scripps Research Institute has described
>>>>>the cellular mechanism underlying the brain's response to alcohol,
>>>>>which suggests a possible method for treating alcoholism.
>>>>>
>>>>>This work, published in the latest issue of the journal Science, ties
>>>>>together the effect of the brain peptide corticotropin releasing
>>>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>>>in the amygdala, the so-called pleasure center of the brain, by
>>>>>increasing the transmission of one particular neurotransmitter called
>>>>>gamma amino butyric acid (GABA).
>>>>>
>>>>>"There is a strong relationship between drugs of abuse, stress, and
>>>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>>>led the research.
>>>>>
>>>>>The research suggests that compounds that block CRF receptors might be
>>>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>>>drinking.
>>>>>
>>>>>Drugs that block CRF receptors are already being looked at by
>>>>>scientists as potential treatments for other psychiatric conditions
>>>>>such as depression, panic disorder, and post-traumatic stress
>>>>>disorder--conditions that also involve CRF in the amygdala.
>>>>>
>>>>>In the latest research, Siggins and his colleagues looked at the
>>>>>effect of alcohol and a common stress-related neuropeptide on a
>>>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>>>Sponsored Links
>>>>>
>>>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>>>3 day program start.www.prometainfo.com
>>>>>
>>>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>>>conventional treatment.www.homerecovery.net
>>>>>
>>>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>>>situation for free.www.PacHills.com
>>>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>>>in every brain region use GABA to fine-tune signaling throughout the
>>>>>nervous system.
>>>>>
>>>>>Scientists have known for several years that alcohol produces many of
>>>>>its intoxicating actions through facilitation of GABA receptor
>>>>>function, and preclinical studies of alcohol dependence have shown
>>>>>that GABAergic activity decreases during alcohol withdrawal and
>>>>>protracted abstinence--the initial post-acute withdrawal period after
>>>>>the cessation of drinking during which a person is especially
>>>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>>>major cause of relapse to alcoholism in individuals undergoing
>>>>>treatment.
>>>>>
>>>>>Previous studies have also shown that alcohol enhances GABA
>>>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>>>
>>>>>CRF is a common peptide in the brain that is responsible for
>>>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>>>the amygdala for activating sympathetic and behavioral responses to
>>>>>stressors. CRF is found in lots of different parts of the brain and is
>>>>>known to be involved in the brain in response to stress, anxiety, and
>>>>>depression.
>>>>>
>>>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>>>is involved in the transition from alcohol use to alcohol dependence.
>>>>>Scripps Research Professor George Koob and his colleagues found
>>>>>recently that levels of CRF increase in brains treated with alcohol.
>>>>>Other studies have shown that CRF levels increase when animals are
>>>>>withdrawing from alcohol as well--a situation analogous to an
>>>>>alcoholic's protracted abstinence.
>>>>>
>>>>>In their latest paper, Siggins and his colleagues show, at the
>>>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>>>GABA neurotransmission is lost.
>>>>>
>>>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>>>effects. During withdrawal, CRF levels increase and these changes may
>>>>>persist for a long time.
>>>>>
>>>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>>>antagonists, or compounds that block the effects of CRF. In the
>>>>>current study, when the scientists applied an antagonist of CRF, they
>>>>>found that alcohol no longer had an effect.
>>>>>
>>>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>>>GABA transmission, it also blocked the effect of alcohol," says
>>>>>Siggins. "The response was totally gone*alcohol no longer did
>>>>>anything.
>>>
>>>
>

[someone in need]

So your saying all the medical doctors and researchers throughout the
world are "mistaken" about alcoholism being a disease?

Addictions such as meth, heroin, crack are also due to inability to
control behavior?

Do you believe at some point that the affected individual loses
control over the addiction?



On Sun, 14 Aug 2005 17:41:56 GMT, WACO
<WasACucumberOnce@NowI'mSober.com> wrote:

>If a schizophrenia was caused by voluntarily ingesting something, yes, but
>it's not. Next comparison of apples to oranges please.
>
>someone in need wrote:
>> So therefore a schitzophrenic really must not take lithium to help
>> control their behavior?
>>
>>
>>
>> On Sat, 13 Aug 2005 17:30:56 GMT, WACO
>> <WasACucumberOnce@NowI'mSober.com> wrote:
>>
>>
>>>someone in need wrote:
>>>
>>>>Perhaps you can be the "control patient" that is you get the lobotomy
>>>>and compare results with those using the CRH blocker.
>>>>
>>>>What is the basis of your comment/conclusion?
>>>
>>>When a person needs a "pill" to justify their behavior and actions its a
>>>sad way to live life. Alcoholism is as much a disease as biting ones nails.
>>>
>>>>
>>>>On Sat, 13 Aug 2005 04:44:00 GMT, WACO
>>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>>
>>>>
>>>>
>>>>>About as effective as a frontal lobotomy?
>>>>>
>>>>>someone in need wrote:
>>>>>
>>>>>
>>>>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>>>>
>>>>>>
>>>>>>
>>>>>>
>>>>>>A team of scientists at The Scripps Research Institute has described
>>>>>>the cellular mechanism underlying the brain's response to alcohol,
>>>>>>which suggests a possible method for treating alcoholism.
>>>>>>
>>>>>>This work, published in the latest issue of the journal Science, ties
>>>>>>together the effect of the brain peptide corticotropin releasing
>>>>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>>>>in the amygdala, the so-called pleasure center of the brain, by
>>>>>>increasing the transmission of one particular neurotransmitter called
>>>>>>gamma amino butyric acid (GABA).
>>>>>>
>>>>>>"There is a strong relationship between drugs of abuse, stress, and
>>>>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>>>>led the research.
>>>>>>
>>>>>>The research suggests that compounds that block CRF receptors might be
>>>>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>>>>drinking.
>>>>>>
>>>>>>Drugs that block CRF receptors are already being looked at by
>>>>>>scientists as potential treatments for other psychiatric conditions
>>>>>>such as depression, panic disorder, and post-traumatic stress
>>>>>>disorder--conditions that also involve CRF in the amygdala.
>>>>>>
>>>>>>In the latest research, Siggins and his colleagues looked at the
>>>>>>effect of alcohol and a common stress-related neuropeptide on a
>>>>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>>>>Sponsored Links
>>>>>>
>>>>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>>>>3 day program start.www.prometainfo.com
>>>>>>
>>>>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>>>>conventional treatment.www.homerecovery.net
>>>>>>
>>>>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>>>>situation for free.www.PacHills.com
>>>>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>>>>in every brain region use GABA to fine-tune signaling throughout the
>>>>>>nervous system.
>>>>>>
>>>>>>Scientists have known for several years that alcohol produces many of
>>>>>>its intoxicating actions through facilitation of GABA receptor
>>>>>>function, and preclinical studies of alcohol dependence have shown
>>>>>>that GABAergic activity decreases during alcohol withdrawal and
>>>>>>protracted abstinence--the initial post-acute withdrawal period after
>>>>>>the cessation of drinking during which a person is especially
>>>>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>>>>major cause of relapse to alcoholism in individuals undergoing
>>>>>>treatment.
>>>>>>
>>>>>>Previous studies have also shown that alcohol enhances GABA
>>>>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>>>>
>>>>>>CRF is a common peptide in the brain that is responsible for
>>>>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>>>>the amygdala for activating sympathetic and behavioral responses to
>>>>>>stressors. CRF is found in lots of different parts of the brain and is
>>>>>>known to be involved in the brain in response to stress, anxiety, and
>>>>>>depression.
>>>>>>
>>>>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>>>>is involved in the transition from alcohol use to alcohol dependence.
>>>>>>Scripps Research Professor George Koob and his colleagues found
>>>>>>recently that levels of CRF increase in brains treated with alcohol.
>>>>>>Other studies have shown that CRF levels increase when animals are
>>>>>>withdrawing from alcohol as well--a situation analogous to an
>>>>>>alcoholic's protracted abstinence.
>>>>>>
>>>>>>In their latest paper, Siggins and his colleagues show, at the
>>>>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>>>>GABA neurotransmission is lost.
>>>>>>
>>>>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>>>>effects. During withdrawal, CRF levels increase and these changes may
>>>>>>persist for a long time.
>>>>>>
>>>>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>>>>antagonists, or compounds that block the effects of CRF. In the
>>>>>>current study, when the scientists applied an antagonist of CRF, they
>>>>>>found that alcohol no longer had an effect.
>>>>>>
>>>>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>>>>GABA transmission, it also blocked the effect of alcohol," says
>>>>>>Siggins. "The response was totally gone*alcohol no longer did
>>>>>>anything.
>>>>
>>>>
>>

[WACO]

No, I'm simply saying "take responsibility for your own actions." I
suppose before the white man came to North America and introduced alcohol
to the natives, the natives already were alcoholic? Following the medical
argument this must be true, regardless of how ludicrous this concept is.

Alcoholism, as with any addiction, is simply behavior based, not
genetically or medically based. And yes, I am saying all the medical
doctors and researchers throughout the world ARE mistaken.

Coming from a long line of alcoholics, I know first hand how behaviors can
be passed on and anyone can quit if they so desire.

someone in need wrote:
> So your saying all the medical doctors and researchers throughout the
> world are "mistaken" about alcoholism being a disease?
>
> Addictions such as meth, heroin, crack are also due to inability to
> control behavior?
>
> Do you believe at some point that the affected individual loses
> control over the addiction?
>
>
>
> On Sun, 14 Aug 2005 17:41:56 GMT, WACO
> <WasACucumberOnce@NowI'mSober.com> wrote:
>
>
>>If a schizophrenia was caused by voluntarily ingesting something, yes, but
>>it's not. Next comparison of apples to oranges please.
>>
>>someone in need wrote:
>>
>>>So therefore a schitzophrenic really must not take lithium to help
>>>control their behavior?
>>>
>>>
>>>
>>>On Sat, 13 Aug 2005 17:30:56 GMT, WACO
>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>
>>>
>>>
>>>>someone in need wrote:
>>>>
>>>>
>>>>>Perhaps you can be the "control patient" that is you get the lobotomy
>>>>>and compare results with those using the CRH blocker.
>>>>>
>>>>>What is the basis of your comment/conclusion?
>>>>
>>>>When a person needs a "pill" to justify their behavior and actions its a
>>>>sad way to live life. Alcoholism is as much a disease as biting ones nails.
>>>>
>>>>
>>>>>On Sat, 13 Aug 2005 04:44:00 GMT, WACO
>>>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>>>
>>>>>
>>>>>
>>>>>
>>>>>>About as effective as a frontal lobotomy?
>>>>>>
>>>>>>someone in need wrote:
>>>>>>
>>>>>>
>>>>>>
>>>>>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>A team of scientists at The Scripps Research Institute has described
>>>>>>>the cellular mechanism underlying the brain's response to alcohol,
>>>>>>>which suggests a possible method for treating alcoholism.
>>>>>>>
>>>>>>>This work, published in the latest issue of the journal Science, ties
>>>>>>>together the effect of the brain peptide corticotropin releasing
>>>>>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>>>>>in the amygdala, the so-called pleasure center of the brain, by
>>>>>>>increasing the transmission of one particular neurotransmitter called
>>>>>>>gamma amino butyric acid (GABA).
>>>>>>>
>>>>>>>"There is a strong relationship between drugs of abuse, stress, and
>>>>>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>>>>>led the research.
>>>>>>>
>>>>>>>The research suggests that compounds that block CRF receptors might be
>>>>>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>>>>>drinking.
>>>>>>>
>>>>>>>Drugs that block CRF receptors are already being looked at by
>>>>>>>scientists as potential treatments for other psychiatric conditions
>>>>>>>such as depression, panic disorder, and post-traumatic stress
>>>>>>>disorder--conditions that also involve CRF in the amygdala.
>>>>>>>
>>>>>>>In the latest research, Siggins and his colleagues looked at the
>>>>>>>effect of alcohol and a common stress-related neuropeptide on a
>>>>>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>>>>>Sponsored Links
>>>>>>>
>>>>>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>>>>>3 day program start.www.prometainfo.com
>>>>>>>
>>>>>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>>>>>conventional treatment.www.homerecovery.net
>>>>>>>
>>>>>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>>>>>situation for free.www.PacHills.com
>>>>>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>>>>>in every brain region use GABA to fine-tune signaling throughout the
>>>>>>>nervous system.
>>>>>>>
>>>>>>>Scientists have known for several years that alcohol produces many of
>>>>>>>its intoxicating actions through facilitation of GABA receptor
>>>>>>>function, and preclinical studies of alcohol dependence have shown
>>>>>>>that GABAergic activity decreases during alcohol withdrawal and
>>>>>>>protracted abstinence--the initial post-acute withdrawal period after
>>>>>>>the cessation of drinking during which a person is especially
>>>>>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>>>>>major cause of relapse to alcoholism in individuals undergoing
>>>>>>>treatment.
>>>>>>>
>>>>>>>Previous studies have also shown that alcohol enhances GABA
>>>>>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>>>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>>>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>>>>>
>>>>>>>CRF is a common peptide in the brain that is responsible for
>>>>>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>>>>>the amygdala for activating sympathetic and behavioral responses to
>>>>>>>stressors. CRF is found in lots of different parts of the brain and is
>>>>>>>known to be involved in the brain in response to stress, anxiety, and
>>>>>>>depression.
>>>>>>>
>>>>>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>>>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>>>>>is involved in the transition from alcohol use to alcohol dependence.
>>>>>>>Scripps Research Professor George Koob and his colleagues found
>>>>>>>recently that levels of CRF increase in brains treated with alcohol.
>>>>>>>Other studies have shown that CRF levels increase when animals are
>>>>>>>withdrawing from alcohol as well--a situation analogous to an
>>>>>>>alcoholic's protracted abstinence.
>>>>>>>
>>>>>>>In their latest paper, Siggins and his colleagues show, at the
>>>>>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>>>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>>>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>>>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>>>>>GABA neurotransmission is lost.
>>>>>>>
>>>>>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>>>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>>>>>effects. During withdrawal, CRF levels increase and these changes may
>>>>>>>persist for a long time.
>>>>>>>
>>>>>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>>>>>antagonists, or compounds that block the effects of CRF. In the
>>>>>>>current study, when the scientists applied an antagonist of CRF, they
>>>>>>>found that alcohol no longer had an effect.
>>>>>>>
>>>>>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>>>>>GABA transmission, it also blocked the effect of alcohol," says
>>>>>>>Siggins. "The response was totally gone*alcohol no longer did
>>>>>>>anything.
>>>>>
>>>>>
>

[Gregg Fowler]

WACO wrote:
> No, I'm simply saying "take responsibility for your own actions." I
> suppose before the white man came to North America and introduced
> alcohol to the natives, the natives already were alcoholic? Following
> the medical argument this must be true, regardless of how ludicrous this
> concept is.

Dried beans isn't bean soup either, but you can't make it without them.
If you have the dried beans though it just takes a little water.

[someone in need]

On Sun, 14 Aug 2005 22:53:01 GMT, WACO
<WasACucumberOnce@NowI'mSober.com> wrote:

>No, I'm simply saying "take responsibility for your own actions." I
>suppose before the white man came to North America and introduced alcohol
>to the natives, the natives already were alcoholic? Following the medical
>argument this must be true, regardless of how ludicrous this concept is.
>




The allopathic medical theory is NOT limited to genetics. It is
multifactorial

environmental
psychologic
social




The fact that addiction catches people of ALL socio-economic and
educational backgrounds would argue against your suggestion of
willpower.

Hows about the physician, attorney, judge, artist, actor,actress with
tremendous motivation and willpower to succeed, be unable to not
succumb to a simple liquid ???????????????????????????

























>Alcoholism, as with any addiction, is simply behavior based, not
>genetically or medically based. And yes, I am saying all the medical
>doctors and researchers throughout the world ARE mistaken.
>
>Coming from a long line of alcoholics, I know first hand how behaviors can
>be passed on and anyone can quit if they so desire.
>
>someone in need wrote:
>> So your saying all the medical doctors and researchers throughout the
>> world are "mistaken" about alcoholism being a disease?
>>
>> Addictions such as meth, heroin, crack are also due to inability to
>> control behavior?
>>
>> Do you believe at some point that the affected individual loses
>> control over the addiction?
>>
>>
>>
>> On Sun, 14 Aug 2005 17:41:56 GMT, WACO
>> <WasACucumberOnce@NowI'mSober.com> wrote:
>>
>>
>>>If a schizophrenia was caused by voluntarily ingesting something, yes, but
>>>it's not. Next comparison of apples to oranges please.
>>>
>>>someone in need wrote:
>>>
>>>>So therefore a schitzophrenic really must not take lithium to help
>>>>control their behavior?
>>>>
>>>>
>>>>
>>>>On Sat, 13 Aug 2005 17:30:56 GMT, WACO
>>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>>
>>>>
>>>>
>>>>>someone in need wrote:
>>>>>
>>>>>
>>>>>>Perhaps you can be the "control patient" that is you get the lobotomy
>>>>>>and compare results with those using the CRH blocker.
>>>>>>
>>>>>>What is the basis of your comment/conclusion?
>>>>>
>>>>>When a person needs a "pill" to justify their behavior and actions its a
>>>>>sad way to live life. Alcoholism is as much a disease as biting ones nails.
>>>>>
>>>>>
>>>>>>On Sat, 13 Aug 2005 04:44:00 GMT, WACO
>>>>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>>>>
>>>>>>
>>>>>>
>>>>>>
>>>>>>>About as effective as a frontal lobotomy?
>>>>>>>
>>>>>>>someone in need wrote:
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>A team of scientists at The Scripps Research Institute has described
>>>>>>>>the cellular mechanism underlying the brain's response to alcohol,
>>>>>>>>which suggests a possible method for treating alcoholism.
>>>>>>>>
>>>>>>>>This work, published in the latest issue of the journal Science, ties
>>>>>>>>together the effect of the brain peptide corticotropin releasing
>>>>>>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>>>>>>in the amygdala, the so-called pleasure center of the brain, by
>>>>>>>>increasing the transmission of one particular neurotransmitter called
>>>>>>>>gamma amino butyric acid (GABA).
>>>>>>>>
>>>>>>>>"There is a strong relationship between drugs of abuse, stress, and
>>>>>>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>>>>>>led the research.
>>>>>>>>
>>>>>>>>The research suggests that compounds that block CRF receptors might be
>>>>>>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>>>>>>drinking.
>>>>>>>>
>>>>>>>>Drugs that block CRF receptors are already being looked at by
>>>>>>>>scientists as potential treatments for other psychiatric conditions
>>>>>>>>such as depression, panic disorder, and post-traumatic stress
>>>>>>>>disorder--conditions that also involve CRF in the amygdala.
>>>>>>>>
>>>>>>>>In the latest research, Siggins and his colleagues looked at the
>>>>>>>>effect of alcohol and a common stress-related neuropeptide on a
>>>>>>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>>>>>>Sponsored Links
>>>>>>>>
>>>>>>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>>>>>>3 day program start.www.prometainfo.com
>>>>>>>>
>>>>>>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>>>>>>conventional treatment.www.homerecovery.net
>>>>>>>>
>>>>>>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>>>>>>situation for free.www.PacHills.com
>>>>>>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>>>>>>in every brain region use GABA to fine-tune signaling throughout the
>>>>>>>>nervous system.
>>>>>>>>
>>>>>>>>Scientists have known for several years that alcohol produces many of
>>>>>>>>its intoxicating actions through facilitation of GABA receptor
>>>>>>>>function, and preclinical studies of alcohol dependence have shown
>>>>>>>>that GABAergic activity decreases during alcohol withdrawal and
>>>>>>>>protracted abstinence--the initial post-acute withdrawal period after
>>>>>>>>the cessation of drinking during which a person is especially
>>>>>>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>>>>>>major cause of relapse to alcoholism in individuals undergoing
>>>>>>>>treatment.
>>>>>>>>
>>>>>>>>Previous studies have also shown that alcohol enhances GABA
>>>>>>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>>>>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>>>>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>>>>>>
>>>>>>>>CRF is a common peptide in the brain that is responsible for
>>>>>>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>>>>>>the amygdala for activating sympathetic and behavioral responses to
>>>>>>>>stressors. CRF is found in lots of different parts of the brain and is
>>>>>>>>known to be involved in the brain in response to stress, anxiety, and
>>>>>>>>depression.
>>>>>>>>
>>>>>>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>>>>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>>>>>>is involved in the transition from alcohol use to alcohol dependence.
>>>>>>>>Scripps Research Professor George Koob and his colleagues found
>>>>>>>>recently that levels of CRF increase in brains treated with alcohol.
>>>>>>>>Other studies have shown that CRF levels increase when animals are
>>>>>>>>withdrawing from alcohol as well--a situation analogous to an
>>>>>>>>alcoholic's protracted abstinence.
>>>>>>>>
>>>>>>>>In their latest paper, Siggins and his colleagues show, at the
>>>>>>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>>>>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>>>>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>>>>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>>>>>>GABA neurotransmission is lost.
>>>>>>>>
>>>>>>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>>>>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>>>>>>effects. During withdrawal, CRF levels increase and these changes may
>>>>>>>>persist for a long time.
>>>>>>>>
>>>>>>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>>>>>>antagonists, or compounds that block the effects of CRF. In the
>>>>>>>>current study, when the scientists applied an antagonist of CRF, they
>>>>>>>>found that alcohol no longer had an effect.
>>>>>>>>
>>>>>>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>>>>>>GABA transmission, it also blocked the effect of alcohol," says
>>>>>>>>Siggins. "The response was totally gone*alcohol no longer did
>>>>>>>>anything.
>>>>>>
>>>>>>
>>

[someone in need]

If you indeed have the willpower to quit and recover my hat is off to
you. You have my deepest respect and admiration.




On Sun, 14 Aug 2005 22:53:01 GMT, WACO
<WasACucumberOnce@NowI'mSober.com> wrote:

>No, I'm simply saying "take responsibility for your own actions." I
>suppose before the white man came to North America and introduced alcohol
>to the natives, the natives already were alcoholic? Following the medical
>argument this must be true, regardless of how ludicrous this concept is.
>
>Alcoholism, as with any addiction, is simply behavior based, not
>genetically or medically based. And yes, I am saying all the medical
>doctors and researchers throughout the world ARE mistaken.
>
>Coming from a long line of alcoholics, I know first hand how behaviors can
>be passed on and anyone can quit if they so desire.
>
>someone in need wrote:
>> So your saying all the medical doctors and researchers throughout the
>> world are "mistaken" about alcoholism being a disease?
>>
>> Addictions such as meth, heroin, crack are also due to inability to
>> control behavior?
>>
>> Do you believe at some point that the affected individual loses
>> control over the addiction?
>>
>>
>>
>> On Sun, 14 Aug 2005 17:41:56 GMT, WACO
>> <WasACucumberOnce@NowI'mSober.com> wrote:
>>
>>
>>>If a schizophrenia was caused by voluntarily ingesting something, yes, but
>>>it's not. Next comparison of apples to oranges please.
>>>
>>>someone in need wrote:
>>>
>>>>So therefore a schitzophrenic really must not take lithium to help
>>>>control their behavior?
>>>>
>>>>
>>>>
>>>>On Sat, 13 Aug 2005 17:30:56 GMT, WACO
>>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>>
>>>>
>>>>
>>>>>someone in need wrote:
>>>>>
>>>>>
>>>>>>Perhaps you can be the "control patient" that is you get the lobotomy
>>>>>>and compare results with those using the CRH blocker.
>>>>>>
>>>>>>What is the basis of your comment/conclusion?
>>>>>
>>>>>When a person needs a "pill" to justify their behavior and actions its a
>>>>>sad way to live life. Alcoholism is as much a disease as biting ones nails.
>>>>>
>>>>>
>>>>>>On Sat, 13 Aug 2005 04:44:00 GMT, WACO
>>>>>><WasACucumberOnce@NowI'mSober.com> wrote:
>>>>>>
>>>>>>
>>>>>>
>>>>>>
>>>>>>>About as effective as a frontal lobotomy?
>>>>>>>
>>>>>>>someone in need wrote:
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>>Alcohol Effects Can Be Blocked, Scientists Say
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>A team of scientists at The Scripps Research Institute has described
>>>>>>>>the cellular mechanism underlying the brain's response to alcohol,
>>>>>>>>which suggests a possible method for treating alcoholism.
>>>>>>>>
>>>>>>>>This work, published in the latest issue of the journal Science, ties
>>>>>>>>together the effect of the brain peptide corticotropin releasing
>>>>>>>>factor (CRF) with alcohol. Both appear to influence neurotransmission
>>>>>>>>in the amygdala, the so-called pleasure center of the brain, by
>>>>>>>>increasing the transmission of one particular neurotransmitter called
>>>>>>>>gamma amino butyric acid (GABA).
>>>>>>>>
>>>>>>>>"There is a strong relationship between drugs of abuse, stress, and
>>>>>>>>the amygdala," says Neuropharmacology Professor George Siggins, who
>>>>>>>>led the research.
>>>>>>>>
>>>>>>>>The research suggests that compounds that block CRF receptors might be
>>>>>>>>a potential new therapeutic for alcoholics, who struggle to stop
>>>>>>>>drinking.
>>>>>>>>
>>>>>>>>Drugs that block CRF receptors are already being looked at by
>>>>>>>>scientists as potential treatments for other psychiatric conditions
>>>>>>>>such as depression, panic disorder, and post-traumatic stress
>>>>>>>>disorder--conditions that also involve CRF in the amygdala.
>>>>>>>>
>>>>>>>>In the latest research, Siggins and his colleagues looked at the
>>>>>>>>effect of alcohol and a common stress-related neuropeptide on a
>>>>>>>>neurotransmitter called gamma amino butyric acid (GABA).
>>>>>>>>Sponsored Links
>>>>>>>>
>>>>>>>>Meth addiction treatmentMedical approach for treating meth addiction.
>>>>>>>>3 day program start.www.prometainfo.com
>>>>>>>>
>>>>>>>>Home Addiction RecoveryEffective, affordable, confidential option to
>>>>>>>>conventional treatment.www.homerecovery.net
>>>>>>>>
>>>>>>>>Drug Addiction HelpWe will help you find solutions for your abuse
>>>>>>>>situation for free.www.PacHills.com
>>>>>>>>GABA is the main inhibitory neurotransmitter in the brain, and neurons
>>>>>>>>in every brain region use GABA to fine-tune signaling throughout the
>>>>>>>>nervous system.
>>>>>>>>
>>>>>>>>Scientists have known for several years that alcohol produces many of
>>>>>>>>its intoxicating actions through facilitation of GABA receptor
>>>>>>>>function, and preclinical studies of alcohol dependence have shown
>>>>>>>>that GABAergic activity decreases during alcohol withdrawal and
>>>>>>>>protracted abstinence--the initial post-acute withdrawal period after
>>>>>>>>the cessation of drinking during which a person is especially
>>>>>>>>vulnerable to relapse. These GABAergic activity changes are probably a
>>>>>>>>major cause of relapse to alcoholism in individuals undergoing
>>>>>>>>treatment.
>>>>>>>>
>>>>>>>>Previous studies have also shown that alcohol enhances GABA
>>>>>>>>neurotransmission in the amygdala, the so-called pleasure center of
>>>>>>>>the brain. Interestingly, the brain corticotropin releasing factor
>>>>>>>>(CRF) stress system also increases GABA transmission in the amygdala.
>>>>>>>>
>>>>>>>>CRF is a common peptide in the brain that is responsible for
>>>>>>>>activating the hypothalamic-pituitary-adrenal stress response and in
>>>>>>>>the amygdala for activating sympathetic and behavioral responses to
>>>>>>>>stressors. CRF is found in lots of different parts of the brain and is
>>>>>>>>known to be involved in the brain in response to stress, anxiety, and
>>>>>>>>depression.
>>>>>>>>
>>>>>>>>Significantly, the CRF system also seems to be central to alcoholism,
>>>>>>>>and scientists at Scripps Research and elsewhere have shown that CRF
>>>>>>>>is involved in the transition from alcohol use to alcohol dependence.
>>>>>>>>Scripps Research Professor George Koob and his colleagues found
>>>>>>>>recently that levels of CRF increase in brains treated with alcohol.
>>>>>>>>Other studies have shown that CRF levels increase when animals are
>>>>>>>>withdrawing from alcohol as well--a situation analogous to an
>>>>>>>>alcoholic's protracted abstinence.
>>>>>>>>
>>>>>>>>In their latest paper, Siggins and his colleagues show, at the
>>>>>>>>cellular level, how alcohol and CRF interact. When neurons are exposed
>>>>>>>>to alcohol, says Siggins, they release CRF, and this causes the
>>>>>>>>release of GABA in the amygdala. And when the CRF receptor is removed
>>>>>>>>altogether (by genetic knock out), the effect of alcohol and CRF on
>>>>>>>>GABA neurotransmission is lost.
>>>>>>>>
>>>>>>>>Siggins and his colleagues say that this suggests a cellular mechanism
>>>>>>>>underlying involvement of CRF in alcohol's behavioral and motivational
>>>>>>>>effects. During withdrawal, CRF levels increase and these changes may
>>>>>>>>persist for a long time.
>>>>>>>>
>>>>>>>>It also suggests a possible way of treating alcoholism -- using CRF
>>>>>>>>antagonists, or compounds that block the effects of CRF. In the
>>>>>>>>current study, when the scientists applied an antagonist of CRF, they
>>>>>>>>found that alcohol no longer had an effect.
>>>>>>>>
>>>>>>>>"Not only did the antagonists block the effect of CRF in enhancing
>>>>>>>>GABA transmission, it also blocked the effect of alcohol," says
>>>>>>>>Siggins. "The response was totally gone*alcohol no longer did
>>>>>>>>anything.
>>>>>>
>>>>>>
>>

[Robert McGregor]

"someone in need" <nospamplease@somewhere.com> wrote in message
news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
> So your saying all the medical doctors and researchers throughout
> the world are "mistaken" about alcoholism being a disease?
>

Apart from the reality that medical doctors and researchers
throughout the world disagree amongst themselves, the "alcoholism is
a disease" concept is certainly a great insurance, and possibly
funding scam.

Bob
In 1960 at a convention of the National Clergy Conference on
Alcoholism, Bill Wilson, founder of Alcoholics anonymous said: “We
have never called alcoholism a disease because, technically speaking,
it is not a disease entity. “

[someone in need]

On Tue, 16 Aug 2005 08:11:30 +1000, "Robert McGregor"
<robert_mcgregor@knickers.yahoo.com.au> wrote:

>"someone in need" <nospamplease@somewhere.com> wrote in message
>news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
>> So your saying all the medical doctors and researchers throughout
>> the world are "mistaken" about alcoholism being a disease?
>>
>
>Apart from the reality that medical doctors and researchers
>throughout the world disagree amongst themselves, the "alcoholism is
>a disease" concept is certainly a great insurance, and possibly
>funding scam.
>
>Bob
>In 1960 at a convention of the National Clergy Conference on
>Alcoholism, Bill Wilson, founder of Alcoholics anonymous said: “We
>have never called alcoholism a disease because, technically speaking,
>it is not a disease entity. “
>
>
>

Correct me ifI am wrong in believing the concensus among the medical
community greatly favors the disease model.



One could argue in many cases that high blood pressure is NOT a
disease in that lifestyly modifications can eliminate it without any
need for medication.

[Robert McGregor]

"someone in need" <nospamplease@somewhere.com> wrote in message
news:2g82g19nbp3ngj08v88phs233h45ii4k9j@4ax.com...
> On Tue, 16 Aug 2005 08:11:30 +1000, "Robert McGregor"
> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>
>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
>>> So your saying all the medical doctors and researchers throughout
>>> the world are "mistaken" about alcoholism being a disease?
>>>
>>
>>Apart from the reality that medical doctors and researchers
>>throughout the world disagree amongst themselves, the "alcoholism
>>is
>>a disease" concept is certainly a great insurance, and possibly
>>funding scam.
>>
>>Bob
>>In 1960 at a convention of the National Clergy Conference on
>>Alcoholism, Bill Wilson, founder of Alcoholics anonymous said: “We
>>have never called alcoholism a disease because, technically
>>speaking,
>>it is not a disease entity. “
>>
>>
>>
>
> Correct me ifI am wrong in believing the concensus among the
> medical
> community greatly favors the disease model.

Your claim was inclusive of "all." I don't believe *anyone* knows
what the consensus is amongst the *medical community* in any country,
let alone world wide.

>
>
>
> One could argue in many cases that high blood pressure is NOT a
> disease in that lifestyly modifications can eliminate it without
> any
> need for medication.
>

One could.

Bob

[someone in need]

On Tue, 16 Aug 2005 10:16:34 +1000, "Robert McGregor"
<robert_mcgregor@knickers.yahoo.com.au> wrote:

>"someone in need" <nospamplease@somewhere.com> wrote in message
>news:2g82g19nbp3ngj08v88phs233h45ii4k9j@4ax.com...
>> On Tue, 16 Aug 2005 08:11:30 +1000, "Robert McGregor"
>> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>>
>>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>>news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
>>>> So your saying all the medical doctors and researchers throughout
>>>> the world are "mistaken" about alcoholism being a disease?
>>>>
>>>
>>>Apart from the reality that medical doctors and researchers
>>>throughout the world disagree amongst themselves, the "alcoholism
>>>is
>>>a disease" concept is certainly a great insurance, and possibly
>>>funding scam.
>>>
>>>Bob
>>>In 1960 at a convention of the National Clergy Conference on
>>>Alcoholism, Bill Wilson, founder of Alcoholics anonymous said: “We
>>>have never called alcoholism a disease because, technically
>>>speaking,
>>>it is not a disease entity. “
>>>
>>>
>>>
>>
>> Correct me ifI am wrong in believing the concensus among the
>> medical
>> community greatly favors the disease model.
>
>Your claim was inclusive of "all." I don't believe *anyone* knows
>what the consensus is amongst the *medical community* in any country,
>let alone world wide.
>
>>
>>
>>
>> One could argue in many cases that high blood pressure is NOT a
>> disease in that lifestyly modifications can eliminate it without
>> any
>> need for medication.
>>
>
>One could.
>
>Bob
>
>
>
Well Bob,

I have been in email communication with addictionologists in Asia who
tell me the disease model is the main one. There are some old
fashioned folks (non medical community) who stick to the ancient
theory of "bad/evil spirits"


I am also aware of the European, Australian, Kiwi and South American
medical community beliefs, essentially the disease model.

I admit I have no knowledge of the beliefs with the African continent.

[Robert McGregor]

"someone in need" <nospamplease@somewhere.com> wrote in message
news:l3e2g196amdk85eg5ag6t2k0pd153rlufm@4ax.com...
> On Tue, 16 Aug 2005 10:16:34 +1000, "Robert McGregor"
> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>
>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>news:2g82g19nbp3ngj08v88phs233h45ii4k9j@4ax.com...
>>> On Tue, 16 Aug 2005 08:11:30 +1000, "Robert McGregor"
>>> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>>>
>>>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>>>news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
>>>>> So your saying all the medical doctors and researchers
>>>>> throughout
>>>>> the world are "mistaken" about alcoholism being a disease?
>>>>>
>>>>
>>>>Apart from the reality that medical doctors and researchers
>>>>throughout the world disagree amongst themselves, the "alcoholism
>>>>is
>>>>a disease" concept is certainly a great insurance, and possibly
>>>>funding scam.
>>>>
>>>>Bob
>>>>In 1960 at a convention of the National Clergy Conference on
>>>>Alcoholism, Bill Wilson, founder of Alcoholics anonymous said:
>>>>“We
>>>>have never called alcoholism a disease because, technically
>>>>speaking,
>>>>it is not a disease entity. “
>>>>
>>>>
>>>>
>>>
>>> Correct me ifI am wrong in believing the concensus among the
>>> medical
>>> community greatly favors the disease model.
>>
>>Your claim was inclusive of "all." I don't believe *anyone* knows
>>what the consensus is amongst the *medical community* in any
>>country,
>>let alone world wide.
>>
>>>
>>>
>>>
>>> One could argue in many cases that high blood pressure is NOT a
>>> disease in that lifestyly modifications can eliminate it without
>>> any
>>> need for medication.
>>>
>>
>>One could.
>>
>>Bob
>>
>>
>>
> Well Bob,
>
> I have been in email communication with addictionologists in Asia
> who
> tell me the disease model is the main one. There are some old
> fashioned folks (non medical community) who stick to the ancient
> theory of "bad/evil spirits"

Oh, that's like AA, where only God can help;)

>
>
> I am also aware of the European, Australian, Kiwi and South
> American
> medical community beliefs, essentially the disease model.

Well "someone." Having seen an Australian govt drug and alcohol unit
promote moderation, and send their clients to AA just to show them a
negative example, having seen the same person still heads the D&A
unit, I don't believe you.

I do believe the USA DSM 1V refers to alcohol dependence and alcohol
abuse, rather than alcoholism the disease. I saw no mention of the
disease theory, but a lot about moderation, on the current Australian
govt website.
http://www.alcoholguidelines.gov.au/groups.htm#guideline4

>
> I admit I have no knowledge of the beliefs with the African
> continent.

Although he does live in Africa, I doubt our very own Mias would
bother with this little argument!

Bob

[someone in need]

On Tue, 16 Aug 2005 12:34:21 +1000, "Robert McGregor"
<robert_mcgregor@knickers.yahoo.com.au> wrote:

>
>"someone in need" <nospamplease@somewhere.com> wrote in message
>news:l3e2g196amdk85eg5ag6t2k0pd153rlufm@4ax.com...
>> On Tue, 16 Aug 2005 10:16:34 +1000, "Robert McGregor"
>> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>>
>>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>>news:2g82g19nbp3ngj08v88phs233h45ii4k9j@4ax.com...
>>>> On Tue, 16 Aug 2005 08:11:30 +1000, "Robert McGregor"
>>>> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>>>>
>>>>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>>>>news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
>>>>>> So your saying all the medical doctors and researchers
>>>>>> throughout
>>>>>> the world are "mistaken" about alcoholism being a disease?
>>>>>>
>>>>>
>>>>>Apart from the reality that medical doctors and researchers
>>>>>throughout the world disagree amongst themselves, the "alcoholism
>>>>>is
>>>>>a disease" concept is certainly a great insurance, and possibly
>>>>>funding scam.
>>>>>
>>>>>Bob
>>>>>In 1960 at a convention of the National Clergy Conference on
>>>>>Alcoholism, Bill Wilson, founder of Alcoholics anonymous said:
>>>>>“We
>>>>>have never called alcoholism a disease because, technically
>>>>>speaking,
>>>>>it is not a disease entity. “
>>>>>
>>>>>
>>>>>
>>>>
>>>> Correct me ifI am wrong in believing the concensus among the
>>>> medical
>>>> community greatly favors the disease model.
>>>
>>>Your claim was inclusive of "all." I don't believe *anyone* knows
>>>what the consensus is amongst the *medical community* in any
>>>country,
>>>let alone world wide.
>>>
>>>>
>>>>
>>>>
>>>> One could argue in many cases that high blood pressure is NOT a
>>>> disease in that lifestyly modifications can eliminate it without
>>>> any
>>>> need for medication.
>>>>
>>>
>>>One could.
>>>
>>>Bob
>>>
>>>
>>>
>> Well Bob,
>>
>> I have been in email communication with addictionologists in Asia
>> who
>> tell me the disease model is the main one. There are some old
>> fashioned folks (non medical community) who stick to the ancient
>> theory of "bad/evil spirits"
>
>Oh, that's like AA, where only God can help;)
>
>>
>>
>> I am also aware of the European, Australian, Kiwi and South
>> American
>> medical community beliefs, essentially the disease model.
>
>Well "someone." Having seen an Australian govt drug and alcohol unit
>promote moderation, and send their clients to AA just to show them a
>negative example, having seen the same person still heads the D&A
>unit, I don't believe you.
>
>I do believe the USA DSM 1V refers to alcohol dependence and alcohol
>abuse, rather than alcoholism the disease. I saw no mention of the
>disease theory, but a lot about moderation, on the current Australian
>govt website.
>http://www.alcoholguidelines.gov.au/groups.htm#guideline4
>
>>
>> I admit I have no knowledge of the beliefs with the African
>> continent.
>
>Although he does live in Africa, I doubt our very own Mias would
>bother with this little argument!
>
>Bob
>
>


"The disease/abstinence model was championed by those people managing
community-controlled residential services. These were, and are, run on
strict lines which insist that all workers, managers and directors
should be abstinent." exerp from
http://www.peele.net/lib/brady.html




What has apparently happened in Australia is the government is very
sensitive to Aboriginal issues, beliefs, and culture, while at the
same time, the allopathis medical/rehab community sees the
disease/abstinence model for the most part. The above webpage is very
interesting and worth a read.

I can't find the url but I recall seeing an Aussie doctor discussion
forum n which they view it as a disease. I am sure there exists some
controversy as everywhere, but the Aussie medical system is very
smilar to that of the usa.

[someone in need]

On Tue, 16 Aug 2005 07:10:25 GMT, someone in need
<nospamplease@somewhere.com> wrote:

>On Tue, 16 Aug 2005 12:34:21 +1000, "Robert McGregor"
><robert_mcgregor@knickers.yahoo.com.au> wrote:
>
>>
>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>news:l3e2g196amdk85eg5ag6t2k0pd153rlufm@4ax.com...
>>> On Tue, 16 Aug 2005 10:16:34 +1000, "Robert McGregor"
>>> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>>>
>>>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>>>news:2g82g19nbp3ngj08v88phs233h45ii4k9j@4ax.com...
>>>>> On Tue, 16 Aug 2005 08:11:30 +1000, "Robert McGregor"
>>>>> <robert_mcgregor@knickers.yahoo.com.au> wrote:
>>>>>
>>>>>>"someone in need" <nospamplease@somewhere.com> wrote in message
>>>>>>news:548vf15trh0qsa9ma57qtc5ms02rc4rsaq@4ax.com
>>>>>>> So your saying all the medical doctors and researchers
>>>>>>> throughout
>>>>>>> the world are "mistaken" about alcoholism being a disease?
>>>>>>>
>>>>>>
>>>>>>Apart from the reality that medical doctors and researchers
>>>>>>throughout the world disagree amongst themselves, the "alcoholism
>>>>>>is
>>>>>>a disease" concept is certainly a great insurance, and possibly
>>>>>>funding scam.
>>>>>>
>>>>>>Bob
>>>>>>In 1960 at a convention of the National Clergy Conference on
>>>>>>Alcoholism, Bill Wilson, founder of Alcoholics anonymous said:
>>>>>>“We
>>>>>>have never called alcoholism a disease because, technically
>>>>>>speaking,
>>>>>>it is not a disease entity. “
>>>>>>
>>>>>>
>>>>>>
>>>>>
>>>>> Correct me ifI am wrong in believing the concensus among the
>>>>> medical
>>>>> community greatly favors the disease model.
>>>>
>>>>Your claim was inclusive of "all." I don't believe *anyone* knows
>>>>what the consensus is amongst the *medical community* in any
>>>>country,
>>>>let alone world wide.
>>>>
>>>>>
>>>>>
>>>>>
>>>>> One could argue in many cases that high blood pressure is NOT a
>>>>> disease in that lifestyly modifications can eliminate it without
>>>>> any
>>>>> need for medication.
>>>>>
>>>>
>>>>One could.
>>>>
>>>>Bob
>>>>
>>>>
>>>>
>>> Well Bob,
>>>
>>> I have been in email communication with addictionologists in Asia
>>> who
>>> tell me the disease model is the main one. There are some old
>>> fashioned folks (non medical community) who stick to the ancient
>>> theory of "bad/evil spirits"
>>
>>Oh, that's like AA, where only God can help;)
>>
>>>
>>>
>>> I am also aware of the European, Australian, Kiwi and South
>>> American
>>> medical community beliefs, essentially the disease model.
>>
>>Well "someone." Having seen an Australian govt drug and alcohol unit
>>promote moderation, and send their clients to AA just to show them a
>>negative example, having seen the same person still heads the D&A
>>unit, I don't believe you.
>>
>>I do believe the USA DSM 1V refers to alcohol dependence and alcohol
>>abuse, rather than alcoholism the disease. I saw no mention of the
>>disease theory, but a lot about moderation, on the current Australian
>>govt website.
>>http://www.alcoholguidelines.gov.au/groups.htm#guideline4
>>
>>>
>>> I admit I have no knowledge of the beliefs with the African
>>> continent.
>>
>>Although he does live in Africa, I doubt our very own Mias would
>>bother with this little argument!
>>
>>Bob
>>
>>
>
>
>"The disease/abstinence model was championed by those people managing
>community-controlled residential services. These were, and are, run on
>strict lines which insist that all workers, managers and directors
>should be abstinent." exerp from
>http://www.peele.net/lib/brady.html
>
>
>
>
>What has apparently happened in Australia is the government is very
>sensitive to Aboriginal issues, beliefs, and culture, while at the
>same time, the allopathis medical/rehab community sees the
>disease/abstinence model for the most part. The above webpage is very
>interesting and worth a read.
>
>I can't find the url but I recall seeing an Aussie doctor discussion
>forum n which they view it as a disease. I am sure there exists some
>controversy as everywhere, but the Aussie medical system is very
>smilar to that of the usa.
>

Alcoholism is the disease produced by the repeated misuse of ethyl
alcohol. It is a Primary disease: it is not caused by some underlying
pyschological or moral flaw. It is a Chronic disease: it does not go
away with time. It is a Progressive disease: it does not improve as
long as one continues to drink. It is a potentially Fatal disease, if
the drinking is not interrupted.

A primary characteristic of an alcoholic is a loss of control- once an
alcoholic starts to drink, he or she is not able to predict how, when,
or if he or she will be able to stop.

There are at least 300,000 alcoholics in Australia and 1 person in 10
who drinks at all will become an alcoholic. 1,600,000 Australians are
affected either personally, or within their family by abuse of
alcohol.

http://members.optusnet.com.au/~apfdfy/Teens.html

[you bore me]

I met this man last year at an AA reunion:

http://www.addictiondoctor.com/dm.html

He has been working with Calif. lawyers to
get addiction classified as a legal argument
in certain circumstances (not DWI).

[rosie read n' post]

"someone in need" <nospamplease@somewhere.com> wrote in message
news:2g82g19nbp3ngj08v88phs233h45ii4k9j@4ax.com...
>
> Correct me if I am wrong in believing the concensus among the medical
> community greatly favors the disease model.
>

you are correct!
just as diabetes, high blood pressure etc etc etc

[someone in need]

On 16 Aug 2005 05:07:38 -0700, "you bore me" <gwbdopesmoker@yahoo.com>
wrote:

>
>I met this man last year at an AA reunion:
>
>http://www.addictiondoctor.com/dm.html
>
>He has been working with Calif. lawyers to
>get addiction classified as a legal argument
>in certain circumstances (not DWI).



I recall when I took the car keys away from the alcoholic in my
family. She hated me but prior to that she had exhibited ZERO
judgement in knowing when to drive.

You would think that when a person needs to hold the wall in order to
walk they would know driving is "out of the question"