Central Nervous System (CNS)
****
"Folic acid is found in high concentrations in the CNS where it is
involved in the metabolism (via methylation) of long chain fatty acids
and phospholipids that make neurotransmitters (e.g.: serotonin and
dopamine) and hormones to help regulate brain function, such as mood,
sleep and appetite (Bottiglieri T, 2000).**

It is essential for the proper formation of the brain, spinal cord, and
nerve cells in the embryo, and helps to maintain them in the adult.*
Closure of the neural tube in the fetus during the fourth week of
gestation cannot be completed without it (Northrup H, 2000).* Together
with cobalamin (B12), folic acid helps make the protective myelin sheath
formed by glia cells (oligodendrocytes in the CNS or Schwann cells in
the peripheral nervous system), whose long arms wrap around axons of
nerve fibers allowing nerve impulses to be transmitted (through the
nodes of Ranvier) at phenomenal speeds compared to unmylinated ones."

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